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1

A selective type 4 phosphodiesterase inhibitor, T-440, modulates intracellular cyclic AMP level and interleukin-2 production of Jurkat cells

Osamu Kaminuma, Akio Mori, Kazuteru Wada, Hideo Kikkawa, Katsuo Ikezawa, Matsunobu Suko, Hirokazu Okudaira

Journal:

Immunopharmacology

Year:

1998

Language:

english

File:

PDF, 132 KB

english, 1998

2

Evidence that cyclosporin A and dexamethasone inhibit allergic airway eosinophilic inflammation via suppression of interleukin-5 synthesis by T cells

Aya Nakata, Osamu Kaminuma, Akio Mori, Koji Ogawa, Hideo Kikkawa, Kazuaki Naito, Katsuo Ikezawa, Matsunobu Suko, Hirokazu Okudaira

Journal:

British Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 338 KB

english, 1998

3

Inhibition of Airway Inflammation in rDer f 2-Sensitized Mice by Oral Administration of Recombinant Der f 2

Masaaki Yasue, Toyokazu Yokota, Yoshio Kajiwara, Matsunobu Suko, Hirokazu Okudaira

Journal:

Cellular Immunology

Year:

1997

Language:

english

File:

PDF, 208 KB

english, 1997

4

Antigen-nonspecific and specific suppression of lymphokine production in desensitized guinea pigs

Kazuo Kobayashi, Matsunobu Suko, Takeshi Yoshida, Stanley Cohen

Journal:

Cellular Immunology

Year:

1986

Language:

english

File:

PDF, 778 KB

english, 1986

5

The effect of smoking on 8-hydroxydeoxyguanosine levels in human lung DNA

Haruo Kiyosawa, Matsunobu Suko, Toshiaki Takaishi, Hiroshi Morita, Hirokazu Okudaira, Koji Ito, Hiroshi Kasai, Susumu Nishimura

Journal:

Free Radical Biology and Medicine

Year:

1990

Language:

english

File:

PDF, 123 KB

english, 1990

6

The effect of platelet-activating factor on [14C]aminopyrine uptake by isolated guinea pig parietal cells

Makoto Nogami, Matsunobu Suko, Terumasa Miyamoto

Journal:

Biochemical and Biophysical Research Communications

Year:

1990

Language:

english

File:

PDF, 363 KB

english, 1990

7

Interstitial pneumonitis in autoimmune MRLlpr mice and its treatment with cyclosporin A

Hirokazu Okudaira, Tadaatsu Ogita, Terumasa Miyamoto, Junji Shiga, Matsunobu Suko, Kunio Okudaira, Eiji Terada, Akira Ghoda, Kyoko Terada, Muneo Saito, Tatsuji Nomura

Journal:

Clinical Immunology and Immunopathology

Year:

1986

Language:

english

File:

PDF, 2.49 MB

english, 1986

8

Effect of Fibronectin on the Production of Leukotriene C4 by Eosinophils

Yoshida, Kaneshige, Suko, Matsunobu, Matsuzaki, Go, Sugiyama, Haruhito, Okudaira, Hirokazu, Ito, Koji

Journal:

International Archives of Allergy and Immunology

Year:

1995

File:

PDF, 740 KB

1995

9

A critical role of IL-2 for the production and gene transcription of IL-5 in allergen-specific human T cell clones

Mori, Akio, Suko, Matsunobu, Kaminuma, Osamu, Nishizaki, Yoko, Mikami, Tadashi, Ohmura, Takeo, Hoshino, Akihiko, Inoue, Satoshi, Tsuruoka, Nobuo, Okumura, Yasushi, Sato, Gen, Ito, Koji, Okudaira, Hiro

Journal:

International Immunology

Year:

1996

Language:

english

File:

PDF, 2.20 MB

english, 1996

10

Eosinophils Are Required for the Induction of Bronchial Hyperresponsiveness in a Th Transfer Model of BALB/c Background

Ohtomo, Takayuki, Kaminuma, Osamu, Yamada, Junji, Kitamura, Noriko, Abe, Akemi, Kobayashi, Noriaki, Suko, Matsunobu, Mori, Akio

Journal:

International Archives of Allergy and Immunology

Year:

2010

Language:

english

File:

PDF, 133 KB

english, 2010

11

IL&hyphen;5&hyphen;Producing T Cells that Induce Airway Eosinophilia and Hyperresponsiveness Are Suppressed by Dexamethasone and Cyclosporin A in Mice

Wada, Kazuteru, Kaminuma, Osamu, Mori, Akio, Nakata, Aya, Ogawa, Koji, Kikkawa, Hideo, Ikezawa, Katsuo, Suko, Matsunobu, Okudaira, Hirokazu

Journal:

International Archives of Allergy and Immunology

Year:

1998

Language:

english

File:

PDF, 181 KB

english, 1998

12

Th2-Cell-Mediated Chemokine Synthesis Is Involved in Allergic Airway Inflammation in Mice

Mori, Akio, Ogawa, Koji, Kajiyama, Yuichiro, Suko, Matsunobu, Kaminuma, Osamu

Journal:

International Archives of Allergy and Immunology

Year:

2006

Language:

english

File:

PDF, 84 KB

english, 2006

13

IL-2-Induced IL-13 Production by Allergen-Specific Human Helper T Cell Clones

Hashimoto, Tomomi, Kobayashi, Noriaki, Kajiyama, Yuichiro, Kaminuma, Osamu, Suko, Matsunobu, Mori, Akio

Journal:

International Archives of Allergy and Immunology

Year:

2006

Language:

english

File:

PDF, 103 KB

english, 2006

14

Murine Th Clones Confer Late Asthmatic Response upon Antigen Challenge

Ohtomo, Takayuki, Kaminuma, Osamu, Kitamura, Noriko, Suko, Matsunobu, Kobayashi, Noriaki, Mori, Akio

Journal:

International Archives of Allergy and Immunology

Year:

2009

Language:

english

File:

PDF, 146 KB

english, 2009

15

Evaluation of Cysteinyl Leukotriene-Induced Contraction of Human Cultured Bronchial Smooth Muscle Cells

Kitamura, Noriko, Kaminuma, Osamu, Ohtomo, Takayuki, Kiyokawa, Nobutaka, Kobayashi, Noriaki, Suko, Matsunobu, Mori, Akio

Journal:

International Archives of Allergy and Immunology

Year:

2009

Language:

english

File:

PDF, 187 KB

english, 2009

16

IgE Levels in Nude Mice

Ito, Koji, Ogita, Tadaatsu, Suko, Matsunobu, Mori, Masaki, Kudo, Koichiro, Hayakawa, Tetsuo, Okudaira, Hirokazu, Horiuchi, Yoshihiko

Journal:

International Archives of Allergy and Immunology

Year:

1979

File:

PDF, 919 KB

1979

17

Primary Role of CD4+ T Cells and Supplemental Role of Mast Cells in Allergic Pulmonary Eosinophilia

Ogawa, Koji, Kaminuma, Osamu, Kikkawa, Hideo, Kameda, Rieko, Ikezawa, Katsuo, Suko, Matsunobu, Okudaira, Hirokazu, Akiyama, Kazuo, Mori, Akio

Journal:

International Archives of Allergy and Immunology

Year:

1999

Language:

english

File:

PDF, 304 KB

english, 1999

18

Effect of Formoterol on Allergen-Induced Cytokine Synthesis by Atopic Asthmatics

Hashimoto, Tomomi, Kitamura, Noriko, Kobayashi, Noriaki, Suko, Matsunobu, Kaminuma, Osamu, Mori, Akio

Journal:

International Archives of Allergy and Immunology

Year:

2007

Language:

english

File:

PDF, 118 KB

english, 2007

19

IL-9 Production by Peripheral Blood Mononuclear Cells of Atopic Asthmatics

Umezu-Goto, Makiko, Kajiyama, Yuichiro, Kobayashi, Noriaki, Kaminuma, Osamu, Suko, Matsunobu, Mori, Akio

Journal:

International Archives of Allergy and Immunology

Year:

2007

Language:

english

File:

PDF, 121 KB

english, 2007

20

IL-5 production by CD4 + T cells of asthmatic patients is suppressed by glucocorticoids and the immunosuppressants FK506 and cyclosporin A

Mori, Akio, Suko, Matsunobu, Nishizaki, Yoko, Kaminuma, Osamu, Kobayashi, Shoko, Matsuzaki, Go, Yamamoto, Kazuhiko, Ito, Koji, Tsuruoka, Nobuo, Okudaira, Hirokazu

Journal:

International Immunology

Year:

1995

Language:

english

File:

PDF, 3.73 MB

english, 1995

21

Genetic factors in the treatment of bronchial asthma

Kaminuma, Osamu, Suko, Matsunobu, Mori, Akio

Journal:

Expert Review of Clinical Immunology

Year:

2006

Language:

english

File:

PDF, 386 KB

english, 2006

22

Experimental Pulmonary Eosinophilia in Mice by Ascaris suum Extract

Nogami, Makoto, Suko, Matsunobu, Okudaira, Hirokazu, Miyamoto, Terumasa, Shiga, Junji, Ito, Mamoru, Kasuya, Shiro

Journal:

American Review of Respiratory Disease

Year:

1990

Language:

english

File:

PDF, 819 KB

english, 1990

23

Hypersensitivity Pneumonitis in Athymic Nude Mice: Additional Evidence of T Cell Dependency

Takizawa, Hajime, Ohta, Ken, Horiuchi, Tadashi, Suzuki, Naohito, Ueda, Takashi, Yamaguchi, Masao, Yamashita, Naomi, Ishii, Akira, Suko, Matsunobu, Okudaira, Hirokazu, Shiga, Junji, Miyamoto, Terumasa,

Journal:

American Review of Respiratory Disease

Year:

1992

Language:

english

File:

PDF, 968 KB

english, 1992

24

Cigarette Smoking Induces Formation of 8-Hydroxydeoxyguanosine, One of the Oxidative Dna Damages in Human Peripheral Leukocytes

Kiyosawa, Haruo, Suko, Matsunobu, Okudaira, Hirokazu, Murata, Katsumi, Miyamoto, Erumasa, Chung, Myung-Hee, Kasai, Hiroshi, Nishimura, Susumu

Journal:

Free Radical Research

Year:

1990

Language:

english

File:

PDF, 443 KB

english, 1990

25

Interleukin-4 Gene Expression and IgE Responsiveness

Okudaira, Hirokazu, Mori, Akio, Akiyoshi, Kazuhiko, Yamamoto, Kazuhiko, Suko, Matsunobu, Watanabe, Naohiro, Ito, Mamoru, Takahashi, Koki, Juji, Takeo

Journal:

International Archives of Allergy and Immunology

Year:

1991

Language:

english

File:

PDF, 85 KB

english, 1991

26

Allergens of the House Dust Mite Dermatophagoides farinae. II. Immunological Characterization of Four Allergenic Molecules

Yamashita, Naomi, Haida, Michiko, Suko, Matsunobu, Okudaira, Hirokazu, Miyamoto, Terumasa

Journal:

International Archives of Allergy and Immunology

Year:

1989

File:

PDF, 1.31 MB

1989

27

Regulation of Human IgE Production by Peripheral Blood Mononuclear Cells from Atopic Patients in Mice with Severe Combined Immunodeficiency

lto, Mamoru, Matsuzaki, Go, Uno, Shu, Katakai, Yuko, Suko, Matsunobu, Endo, Sachio, Okudaira, Hirokazu

Journal:

International Archives of Allergy and Immunology

Year:

1992

File:

PDF, 1.31 MB

1992

28

Allergen-Specific Human T Cell Clones Produce lnterleukin-5 upon Stimulation with the Th1 Cytokine lnterleukin-2

Mori, Akio, Suko, Matsunobu, Tsuruoka, Nobuo, Kaminuma, Osamu, Ohmura, Takeo, Nishizaki, Yoko, Ito, Koji, Okudaira, Hirokazu

Journal:

International Archives of Allergy and Immunology

Year:

1995

File:

PDF, 1.08 MB

1995

29

Synthesis of Biologically Active Recombinant Der f II

Yuuki, Toshifumi, Okumura, Yasushi, Ando, Toru, Yamakawa, Hiroshi, Suko, Matsunobu, Haida, Michiko, Dohi, Makoto, Okudaira, Hirokazu

Journal:

International Archives of Allergy and Immunology

Year:

1991

File:

PDF, 908 KB

1991

30

Cellular hypersensitivity to human pancreatic B-cell clone in diabetes mellitus and its relationship to the presence of islet cell antibodies.

MORI, YUTAKA, MATSUDA, IKURO, TSURUOKA, AKIRA, SASAKI, ATSUKO, UTSUNOMIYA, KAZUNORI, ISHII, KENJI, YAMADA, HARUO, TANESE, TOMIO, ISHIKAWA, HIROSHI, SUKO, MATSUNOBU, SHIDA, TAKAO, IKEDA, YOSHIO

Journal:

Endocrinologia Japonica

Year:

1985

Language:

english

File:

PDF, 803 KB

english, 1985

31

An Asthma Patient with Steroid-resistant Decrease in Peak Expiratory Flow after the Great East Japan Earthquake Showing Spontaneous Recovery after 1 Month

Yanagimoto, Shintaro, Haida, Michiko, Suko, Matsunobu

Journal:

Internal Medicine

Year:

2012

Language:

english

File:

PDF, 302 KB

english, 2012

32

10.2169/naika.93.2144

SUKO, MATSUNOBU

Journal:

Nihon Naika Gakkai Zasshi

Year:

2004

File:

PDF, 386 KB

2004

33

IL-2-induced IL-5 synthesis, but not proliferation, of human CD4+ T cells is suppressed by FK506.

Mori, Akio, Suko, Matsunobu, Kaminuma, Osamu, Inoue, Satoshi, Ohmura, T, Hoshino, Akihiko, Asakura, Yumiko, Terada, E, Miyazawa, Keiji, Nosaka, Chihiro, Okumura, Yasushi, Ito, K, Okudaira, H

Journal:

The Journal of Immunology

Year:

1997

Language:

english

File:

PDF, 2.99 MB

english, 1997

34

Interleukin-4 Gene Expression in High and Low IgE Responder Mice

Mori, Akio, Yamamoto, Kazuhiko, Suko, Matsunobu, Watanabe, Naohiro, Ito, Mamoru, Miyamoto, Terumasa, Okudaira, Hirokazu

Journal:

International Archives of Allergy and Immunology

Year:

1990

File:

PDF, 1.15 MB

1990

35

Regulation of lnterleukin-5 Production by Peripheral Blood Mononuclear Cells from Atopic Patients with FK506, Cyclosporin A and Glucocorticoid

Mori, Akio, Suko, Matsunobu, Nishizaki, Yoko, Kaminuma, Osamu, Matsuzaki, Go, lto, Koji, Etoh, Takafumi, Nakagawa, Hidemi, Tsuruoka, Nobuo, Okudaira, Hirokazu

Journal:

International Archives of Allergy and Immunology

Year:

1994

File:

PDF, 1.72 MB

1994

36

Cloning and expression of cDNA coding for the major house dust mite allergen Der f II in Escherichia coli.

YUUKI, Toshifumi, OKUMURA, Yasushi, ANDO, Torn, YAMAKAWA, Hiroshi, SUKO, Matsunobu, HAIDA, Michiko, OKUDAIRA, Hirokazu

Journal:

Agricultural and Biological Chemistry

Year:

1991

Language:

english

File:

PDF, 538 KB

english, 1991

37

Development of Lung Eosinophilic Inflammation by the Infusion of IL-5-Producing T Cell Clones

Kaminuma, Osamu, Mori, Akio, Suko, Matsunobu, Kikkawa, Hideo, Naito, Kazuaki, Okudaira, Hirokazu

Journal:

International Archives of Allergy and Immunology

Year:

1997

Language:

english

File:

PDF, 686 KB

english, 1997

38

Enhanced Production and Gene Expression of lnterleukin-5 in Patients with Bronchial Asthma: Possible Management of Atopic Diseases by Down-Regulation of lnterleukin-5 Gene Transcription

Okudaira, Hirokazu, Mori, Akio, Suko, Matsunobu, Etoh, Takafumi, Nakagawa, Hidemi, Ito, Koji

Journal:

International Archives of Allergy and Immunology

Year:

1995

Language:

english

File:

PDF, 866 KB

english, 1995

39

IgG2 Antibodies Block IgE Antibody-Induced Asthma in Guinea Pigs

Yamauchi, Nobukazu, Ito, Koji, Suko, Matsunobu, Ishii, Akira, Miyamoto, Terumasa

Journal:

International Archives of Allergy and Immunology

Year:

1986

Language:

english

File:

PDF, 740 KB

english, 1986

40

Analysis of Human lnterleukin-5 Gene Transcription by T Cell Clones and Hybridomas

Mori, Akio, Inoue, Satoshi, Mikami, Tadashi, Kaminuma, Osamu, Ohmura, Takeo, Nishizaki, Yoko, Asakura, Yumiko, Suko, Matsunobu, lto, Koji, Okudaira, Hirokazu

Journal:

International Archives of Allergy and Immunology

Year:

1995

Language:

english

File:

PDF, 317 KB

english, 1995

41

A Novel Phosphodiesterase Inhibitor, T-440: Possible Management of Eosinophilic Inflammation by Down-Regulation of lnterleukin-5 Production

Kaminuma, Osamu, Mori, Akio, Suko, Matsunobu, Nishizaki, Yoko, Kikkawa, Hideo, Ikezawa, Katsuo, Okudaira, Hirokazu

Journal:

International Archives of Allergy and Immunology

Year:

1996

Language:

english

File:

PDF, 587 KB

english, 1996

42

Selective Suppression of IL-5 Synthesis by OM-01 – Pinpoint Treatment of Atopic Diseases by IL-5 Gene Transcription Inhibitor

Okudaira, Hirokazu, Mori, Akio, Mikami, Tadashi, Kaminuma, Osamu, Ohmura, Takeo, Hoshino, Akihiko, Suko, Matsunobu

Journal:

International Archives of Allergy and Immunology

Year:

1997

Language:

english

File:

PDF, 619 KB

english, 1997

43

Inhibition of Allergen-Induced Bronchoconstriction in Sensitized Guinea Pigs by Orally Administered Allergen

Ishii, Akira, Ino, Yoshitaka, Haida, Michiko, Dohi, Makoto, Suko, Matsunobu, Morita, Yutaka, Ito, Koji, Okudaira, Hirokazu

Journal:

International Archives of Allergy and Immunology

Year:

1991

Language:

english

File:

PDF, 459 KB

english, 1991

44

Dissection of Human IL-5 Promoter – Essential Role of CLEO Element in Human IL-5 Gene Transcription

Mori, Akio, Kaminuma, Osamu, Mikami, Tadashi, Hoshino, Akihiko, Ohmura, Takeo, Miyazawa, Keiji, Suko, Matsunobu, Okudaira, Hirokazu

Journal:

International Archives of Allergy and Immunology

Year:

1997

Language:

english

File:

PDF, 543 KB

english, 1997

45

Anti-Dermatophagoides farinae type I and II IgE antibodies in allergic rhinitis

Suzaki, Harumi, Matsuzaki, Go, Suko, Matsunobu, Okudaira, Hirokazu, Nomura, Yasuya

Journal:

Allergology International

Year:

1996

Language:

english

File:

PDF, 307 KB

english, 1996

46

Preferential Enhancement of IgE Antibody Formation by Bordetella pertussis

Suko, Matsunobu, Ogita, Tadaatsu, Okudaira, Hirokazu, Horiuchi, Yoshihiko

Journal:

International Archives of Allergy and Immunology

Year:

1977

Language:

english

File:

PDF, 1.10 MB

english, 1977

47

T-Cell-Dependent Accumulation of Eosinophils in the Lung and Its Inhibition by Monoclonal Anti-Interleukin-5

Okudaira, Hirokazu, Nogami, Makoto, Matsuzaki, Go, Dohi, Makoto, Suko, Matsunobu, Kasuya, Shiro, Takatsu, Kiyoshi

Journal:

International Archives of Allergy and Immunology

Year:

1991

Language:

english

File:

PDF, 572 KB

english, 1991

48

Spontaneous Regression in Murine Hypersensitivity Pneumonitis: Lack of Immunological Tolerance

Takizawa, Hajime, Suko, Matsunobu, Kobayashi, Nobuyuki, Ohta, Ken, Shoji, Shunsuke, Horiuchi, Tadashi, Okudaira, Hirokazu, Miyamoto, Terumasa, Shiga, Junji

Journal:

International Archives of Allergy and Immunology

Year:

1989

Language:

english

File:

PDF, 1.56 MB

english, 1989

49

Oral Immunotherapy May Induce T Cell Anergy

Suko, Matsunobu, Mori, Akio, Ito, Koji, Okudaira, Hirokazu

Journal:

International Archives of Allergy and Immunology

Year:

1995

Language:

english

File:

PDF, 632 KB

english, 1995

50

Anti-Dermatophagoides farinae Groups I and II IgE Antibodies in Atopic Patients

Matsuzaki, Go, Shu, Uno, Ando, Tohru, Suko, Matsunobu, Ito, Koji, Okudaira, Hirokazu

Journal:

International Archives of Allergy and Immunology

Year:

1992

Language:

english

File:

PDF, 527 KB

english, 1992

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